​​​​​​​

Type 1 Diabetes Studies in New England:​​​​

     ​N​ew-Onset Diabetes

AG019 and Teplizumab

  • A Study to Assess the Safety and Tolerability of Different Doses of AG019 Administered Alone or in Combination With Teplizumab in Participants With Recently Diagnosed Type 1 Diabetes Mellitus (T1D)

    ​Yale University, New Haven, CT

    Study Website   Recruiting

AVT001

  • A Phase 1 / 2 Double-Blind, Randomized, Placebo Controlled Study of Safety, Tolerability and Potential Efficacy of AVOTRES Cell-Based Therapy (AVT001) in Patients With Type 1 Diabetes

    ​Joslin Diabetes Center, Boston, MA

    Study Website   Recruiting

     ​​​Family Members (At-Risk)

TrialNet Pathway to Prevention

Anti-CD3 Prevention

  • Anti-CD3 mAb (Teplizumab) for Prevention of Diabetes in Relatives At-Risk for Type 1 Diabetes Mellitus
    Dartmouth-Hitchcock, Lebanon, NH
    Joslin Diabetes Center, Boston, MA 
    ​​Yale University, New Haven, CT​​​​​
    Study Website   Not Recruiting

Abatacept Prevention

  • CTLA-4 Ig (Abatacept) for Prevention of Abnormal Glucose Tolerance and Diabetes in Relatives At-Risk for Type 1 Diabetes Mellitus
    Joslin Diabetes Center, Boston, MA 
    ​Yale University, New Haven, CT​​​​​​
    Study Website   Recruiting

Hydroxychloroquine (HCQ)

  • Hydroxychloroquine for Prevention of Abnormal Glucose Tolerance and Diabetes in Individuals At-risk for Type 1 Diabetes Mellitus (T1D)

    ​​Yale University, New Haven, CT​​​​​

    Study Website   Recruiting

​​     Longer Duration of Diabetes

Bone Health in Youth

  • Bone Mineral Accrual and Microarchitecture in Youth With Type 1 Diabetes
    Massachusetts General Hospital, Boston, MA​​​​​
    Study Website   Recruiting

Diabetes, Diet and Brain

  • Dietary Glycemic Index, Brain Function and Food Intake in Patients With Type 1 Diabetes Mellitus
    Boston Children's Hospital, Boston, MA​
    Study Website   Recruiting

ISaAC Study

TANGO

  • Technological Advances in Glucose Management in Older Adults
    ​Joslin Diabetes Center, Boston, MA

    Study Website   Recruiting

TILT

HARPdoc

  • A Hypoglycaemia Awareness Restoration Programme for people with type 1 diabetes and problematic hypoglycaemia persisting despite optimised care

    Joslin Diabetes Center, Boston, MA

    Study Website   Recruiting
​​T1DTri​als.org​​​ is hosted by the Hood Center for Prevention of Childhood Diabetes at Joslin Diabetes Center. Listing of a study on this site does not imply endorsement or review. 
Evaluate the risks and potential benefits of clinical studies and talk to your health care provider before participating in a study. 
The safety and scientific validity of a research study is the responsibility of the study investigators and sponsor. For studies tabbed in blue, contact the study directly for additional information. We can provide additional information only for those studies tabbed in red. For additional information or to add or remove a study contact us via email research@T1DTrials.org or T1DTrials@joslin.harvard.edu or phone (888) 813-8669.  
Copyright © 2016-2019; Last updated April 1st, 2019.